In pursuit of repairing unhealthy hearts, scientists at the Cedars-Sinai Heart Institute in Los Angeles are searching for a biological fix for irregular heartbeats. Their research, published in the January issue of Nature Biotechnology, shows that when the Tbx18 gene is inserted into ordinary heart cells, it transforms them into pacemaker cells, which creates the electrical activity needed to make the heart pump blood. Currently, doctors prescribe medications or insert electronic pacemakers when things go awry. But this research suggests a biological remedy may not be too far away. Researchers hope to conduct clinical trials on humans within the next two to three years, an inspiring development that makes our hearts skip a beat.